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Today's interview is with Dr Lee Know. Dr Know is a licensed naturopathic doctor, recipient of several awards, and has held positions as medical advisor, scientific evaluator, and director of research and development for major organizations. He's the author of Mitochondria and the Future of Medicine (Chelsea Green Publishing, 2018), the Director of Scientific Affairs for Canada, and consultant to other natural health product brands.

1. Your book, "Mitochondria and the Future of Medicine," makes some pretty amazing claims about the importance of mitochondria to our overall health. You go into a lot of detail in the book, but for those who might not be familiar, could you just briefly explain what mitochondria are and what they do for us? The cell is comprised of different organelles: these are distinct structures that carry out specialized functions. The mitochondria is one of these organelles. Their main role is as a powerhouse for the cell: they produce energy. Everything that happens in the body requires an input of energy, and over 90% of that is produced by the mitochondria.
2. Along those lines: can you briefly summarize the Mitochondrial Theory of Aging? This theory has been around for a number of years now. It overcomes some of the issues with previous theories of aging like the free radical theory. It says that the health and function of the mitochondria within our cells is the biological clock. This looks at the health of the mitochondria and their ability to produce energy and meet the demands of a particular cell. There is a process that happens on the inner membrane of the mitochondria called the Electron Transport Chain: these pass electrons from one complex to the next. But if the electrons spill out, they will cause damage to the mitochondrial DNA. When the mitochondrial DNA is damaged, it can't produce proteins in the ETC anymore, and the mitochondrial production of energy will slow down. This will lower cellular health. It's the free radicals generated at the level of the mitochondria that have the greatest impact on aging. Those from exogenous sources have only a minor impact.
   1. Side note here: I thought the fact that babies have more UCPs to keep them warm fascinating! Didn't realize that brown fat was protective against degenerative diseases because the excess energy gets dissipated as heat rather than turned into free radicals, either. Very cool! Can you address what this means for certain populations in terms of exercise (and how important it is, relatively speaking?) Infants are able to maintain body temp bc they have a lot of brown adipose tissue or brown fat. The mitochondria is high in uncoupling proteins. Under normal circumstances, we create energy by the ETC, pumping protons into a space and those protons create ATP. UCPs uncouple the proton gradient and those protons will flow back through other channels. The result is heat. For infants, that's a way for them to generate heat. There's also research going on into how to increase brown fat in adults. People who have low brown fat and UCPs are more overweight. If we can increase this, we'll dissipate the proton gradient. This is how hibernating animals can go all year and hibernate in cold temperatures. This is why they eat such high fat diets to store up energy. Also talks about this with different populations. The Inuit in the far N have more uncoupling proteins than people who live closer to the equator. One of the ways we can increase brown fat is through cold exposure. Our bodies will adapt because of this. If you're from warmer climates, you don't want to generate more heat. This is why hydrotherapy is great!
3. One key insight in your book seems to be the feedback mechanisms involved in the mitochondria itself?and taking antioxidants may hinder this process (at least compared to reducing the free radical leakage in the first place, on uncoupling electrons from ATP production). Can you elaborate on this a bit? The free radicals that matter most are generated at the level of the mitochondria. Free radicals are generally thought to be negative, but in reality they have a positive aspect too. When put into context of what else is going on in the cell, these help our bodies adapt. You don't want to neutralize these. Controlled exposure to oxidative stress can increase life span. Training with exercise, for instance, generates free radicals, but when those are generated in that sense, they send a positive signal. According to the study, antioxidants during the training phase will blunt the response to that training.

1. You mention that the one proven way to extend life is calorie restriction in your book. Tell me a little more about why this is. Calorie restriction means fewer electrons enter the ETC and therefore fewer free radicals are created. This also turns certain genes on and off.
   1. But: CoQ10: this isn't a vitamin, we produce it ourselves. But it becomes more vitamin-like as we age bc our bodies produce less of it. Its role: it's a component of the ETC, accepts electrons from complex 1 and 2 and passes them to complex 3. Availability of CoQ10 can be a bottleneck in mitochondrial efficiency. You want an excess of this bc it's a busy molecule. It lowers in older people, especially people with certain health conditions. There are many studies now that have shown that when you supplement these people with CoQ10, you get the mitochondria working a lot better. Allows the cells to act more efficiently.
   2. Magnesium: numerous studies show that about 70% of the population doesn't even get the RDA amount. This is the minimum amount of a nutrient that prevents a deficiency syndrome in 98% of the population. This is minimum, not optimal amount. Magnesium is a cofactor in many different processes in the body. Many enzymes in the body need magnesium as a cofactor. ATP (Adenosine TriPhosphate) is actually magnesium ATP. Every molecule of ATP is attached to a magnesium. This is very important for energy production. People will often report that they feel less tired when they take it.
2. It seems your two favorite nutrients for mitochondrial support are CoQ10 and Magnesium. Is this true? And can you explain a little about why each is important, and who should be supplementing with them? There are a lot of nutrients out there that are still helpful besides these.
   1. Diastolic BP is the pressure when your cardiovascular system is at rest. This is a function of how elastic your blood vessels are and how well they can relax. Muscle relaxation actually takes more energy than muscle contraction. (An example of this: when we die, we're no longer producing energy and the muscles go into rigor mortis.) We have muscles surrounding all our blood vessels. When they don't have the energy necessary to relax, that's what causes the diastolic number to increase.
3. D-Ribose also gets a spotlight. What are some of the key features that make you consider this supplement for a patient? (And can you explain further the association between ribose and diastolic hypertension?) This is a 5-carbon sugar, not a 6-carbon sugar like glucose or fructose. This is very safe for diabetics and there's a potential that it could even lower blood sugar. D-Ribose is the backbone of the adenosine molecule that creates ATP. It's a critical building block of the molecule. Our bodies normally produce enough of this on its own ? don't necessarily need to supplement it. But in certain circumstances, the body can't produce it fast enough to meet the body's demands. That's why it's often recommended for Chronic Fatigue and fibromyalgia. Because we're constantly in a state where we're depleting adenosine, sometimes people just can't keep up with the demand. D-Ribose can help balance this. The ketogenic diet is very popular, but our bodies use glucose as a starting material to create D-Ribose; so if you're low on carb intake, you're starving the body for the building block for D-Ribose. For anyone going through ketosis, the addition of D-Ribose is helpful.
4. Can you explain the connection between glutamate, excitotoxicity, and declining neuronal cell energy? (And why this means MSG isn't a great idea?) MSG gets converted to glutamate in the body which is an excitatory neurotransmitter. Too much of this causes neurons to be in an excited state for too long a period of time. This adds stress, and the CNS is the most energy-intense system in the body. When you're exposed to glutamate, this will create stress that will lead to the energy molecules like ATP to be depleted. Sometimes with MSG after you eat, you'll have a rapid HR and sweating, which is because of the excitatory effects of glutamate, but then you deplete everything and wear out the neurons, and a few hours later, you get a very low energy level.
   1. Statins: these are the most prescribed drugs in the world to lower cholesterol. Assuming that you believe that cholesterol is an issue to begin with: these block the enzyme that produce cholesterol. This is why it's so effective in lowering cholesterol. The problem is, that same enzyme produces CoQ10. So this induces CoQ10 deficiency and sets you up for cardiovascular disease. Statins have no place in healthcare! If you're looking to lower cholesterol, there are natural ways to do it. But if you are taking them, you should be on CoQ10 too. You should also be on Vit D as well, since statins will also deplete this.
   2. Antibiotics: these are particularly damaging to mitochondria. Mitochondria were once individual bacteria, and antibiotics are great at killing bacteria?so mitochondria are therefore also susceptible. Antibiotics are also way overprescribed. They not only decimate the microbiome, but they can inflict significant damage on the mitochondria.
   3. Tylenol/Acetaminophen. This is considered the biggest cause of liver damage in the US and Canada from accidental overdose. It depletes our bodies' stores of glutathione. Glutathione is an incredibly important source of antioxidant support, and without it, the oxidative damage generated by the ETC can damage the DNA of the mitochondria, causing them to slow down and be less efficient.
5. What would you say are the top two or three most popular drugs that can disrupt mitochondrial function?
6. PQQ can actually stimulate the growth of new mitochondria?! Tell me more about this. (And it's high in chocolate - yay!!) PQQ is another interesting nutrient found in small amounts throughout the food chain. This was the first nutrient to show mitochondrial biogenesis. Prior to seeing this with PQQ, the only way to increase mitochondria was with physical activity. But we see it with PQQ too ? even without exercise.
7. What are other things to avoid (besides pharmaceuticals) to preserve mitochondrial health? Most standard toxins will have an impact: heavy metals, pesticides (another good reason to eat organic!). In a lab setting, some studies look at Parkinson's in a rat model and they use a pesticide to create mitochondrial damage so that they can then study the results! But we willingly consume them. The FDA is not looking at damage to the mitochondria, nor is the USDA. Artificial food colors are damaging as well.
8. Anything I haven't asked you that you want to make sure you communicate to our audience? Exercise is probably the most important thing you can do for your mitochondrial health. This is how our bodies adapt and get stronger. At rest, which is the bulk of the day, the metabolic demand on each individual mitochondria is considerably less. That's why there's the exercise paradox: physical activity does create a lot of free radicals, but those are the "good" ones and allow our bodies to get stronger. This is one reason why athletes have longer and healthier lives. One of the motivating factors for people to get up and get active is to understand the rationale.

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Today's meditation comes from Psalm 86, but we jump all over, from Genesis through Psalms.Download the latest episode of Christian Natural Health!

Dr. Ingels is the author of The Lyme Solution: A 5-Part Plan To Fight The Inflammatory Autoimmune Response And Beat Lyme Disease (get your copy here!), and a respected leader in natural medicine with numerous publications, international lectures and 30 years experience in the healthcare field. Dr. Ingels is a licensed naturopathic physician in the State of Connecticut and a licensed Doctor of Naturopathic Medicine in the State of California. He maintains practices in both states.

Dr. Ingels' practice focuses on environmental medicine with special emphasis on Lyme disease, autism, Pediatric Acute-onset Neuropsychiatric Syndrome (PANS and PANDAS) and chronic immune dysfunction, including allergies, asthma, recurrent or persistent infections and other genetic or acquired immune problems.

1. Antibiotics are still considered the standard treatment for Lyme; even Lyme-literate MDs still use them in high, long-term doses and sometimes via IV. Can you discuss what you've seen clinically with the patients who use this approach, versus those who go for herbs right off the bat? Dr Ingels had Lyme himself, and did the standard course of treatment: 21 days of doxycycline. He got sick just before starting his own practice and was working 10-12 hr days. After 8 mo got symptoms again. He figured it probably wasn't a new tick bite. Changed to other antibiotics. Over 8-9 mo, changed the protocol. He lost 25 lbs. He saw Dr Zhong and began his herbal protocol, and within weeks, pt was 85% better. That was his wake-up call. In acute Lyme, Abx can be very effective. But chronic or persistent state, they seems to do more harm than good. Antibiotics damage the mitochondria, compounding the problems that occur from antibiotics themselves. They have clinical improvement while they're on it, but within weeks to months, they're back to square one. Herbal therapy encompasses a broader scope of what Lyme does to the body, and is not totally focused on the organism. They are also anti-inflammatory, improve circulation, and help brain fog. There is good evidence in the literature ? eventually Lyme becomes autoimmune.
2. Have you seen that prior antibiotic use prolongs the length of time that patients will require herbal treatment? Long-term ABx: have to undo the damage that has occurred. Have to do all the right things to improve gut function: probiotics, glutamine, digestive enzymes, etc. With animal studies: can take up to 6 mo to repopulate after a single round of antibiotics. It's hard to know when we get the gut back to a normal healthy level. He does see MCAS on people who have been on long-term ABx. It's part of the damage to the gut.
3. Your top herbal protocols are Zhang and a modified Cowden, followed by Byron White and Stephen Buhner. These latter two are the ones I have most experience with, largely for price and ease of use. Can you briefly discuss the differences between the four herbal protocols for our listeners? He went through the Zhang protocol himself, and out of all those out there, it's the one that casts the widest net, addressing all the issues that Lyme addresses. It is a complicated medical condition. Chinese herbal medicine as a whole: it's not one herb for one condition. They help balance each other. There's more of an intention behind it. Dr. Zhang started looking at the pharmacology of what the herbs are doing. It addresses the broadest scope of what Lyme does, and there's a lot less herxing. The nature of how the herbs are formulated minimizes this. The biggest down side is cost. He did meet with the company out of CA: makes sure they are free of heavy metals and etc and they are highly concentrated, but this process makes them pricey. A month's supply: $450-500. Dr Cowden herbs: the whole protocol was complicated and hard to follow: 8-12 herbs. But some of the herbs work better than doxycycline, and there are just four of them that are really necessary. He has people go on just those four. People like them bc they're liquids: drops in water, easy to take, don't taste horrible (so it's reasonable for kids) and the cost: $125-130 for 6 weeks. It's more cost-effective for people. Dr Zhang: 80% get clinical improvement, or Cowden: 70%. He's had people who start on one protocol and change to another and feel better. At the end of the day, the protocols all do the same kind of thing. He hasn't used Byron White and Beyond Balance as much: lots of herxing. But these are drop doses, so it's easy for people to do them.
4. For herxing, I generally recommend slowing down herbal treatments, and/or infrared sauna or deep tissue Swedish massage (per Buhner's recommendations). I haven't tried the herbs you list (AI#3 or burbur)?can you speak to their mechanism of action? The AI #3 is anti-inflammatory. Burbur is more about detox: improving these pathways which helps to reduce inflammation. Some people will take burbur every 10-15 minutes. Alkalinizing the body also helps with herxing: reducing allergies and sensitivities. TriSalts: a sodium, potassium, and bicarb formula seems to help. Bicarb alkalinizes the body, and this seems to reduce allergies, autoimmunity, inflammation, etc.
5. You recommend an alkaline diet for your Lyme patients. Why this one? Our bodies function well at an alkaline pH. The rest of the body is very alkaline. All the things in the environment tend to make us very acidic. The down-stream effect is that this creates more inflammation in the body. Dr Ingels found that an alkaline diet clinically is beneficial, but it's something people can follow long-term. The ketogenic diet is hard to sustain long-term. Paleo: tend to eat a lot of meat. With alkaline diet, trying to keep animal protein to 20%. You can eat too much meat! It's hard on the kidneys: too much of this can be an issue.
   1. He had a little boy with classic PANS and had sky-high strep Abs. Started treating for strep and he got a little better but the symptoms were still there. He had been treated for Lyme and thought he was fine. Gave Lyme LDI and he reacted. What he thinks happened in his case: Lyme was still there but strep was the catalyst. The Lyme triggered the autoimmune reaction.
6. You discuss immunotherapy, as well. Can you discuss briefly what it is for the audience? Who makes a good candidate for immunotherapy? When do you add this in? Low-Dose Immunotherapy is a type of therapy designed to modulate the way the immune system reacts to an organism. At a certain point, Lyme becomes autoimmune and this tries to turn that off. Dr Ty Vincent, the founder, had done another therapy called LDA (low dose allergy therapy). He realized that the mechanism by which the immune system reacts to an allergen is similar. LDI has been a game-changer for a lot of patients. Will start people on an herbal protocol first, bc he's not sure we ever 100% get rid of Lyme. We never really know if it's gone. He likes to use herbs to reduce the load in the body first. If there are 1000 bacteria aggravating the body, you can get it down to 100 or 10 and people do feel an improvement. LDI can be applied to any microbe. In can be a game-changer, but in some cases it can be a trainwreck too ? might cause flares. This tells us that the organism for which they are being treated is probably why they feel the way they feel. If you give a dose and they don't flare, it may not be a huge trigger. Once you find out what the right dose is, they have another one every 7-8 weeks. 1.5-2 yrs is normal for treatment. Usually it's not just Lyme: there are other microbes that play a role. Dr Vincent has had 150 docs in N America who have trained with him on how to do it. But this is one of the few therapies that really helps to turn off the autoimmunity.
7. What is your preferred testing for coinfections ? or do you typically go by symptoms? Lyme is a clinical diagnosis. Even the CDC website says that. He used to do this test for a living as a microbiologist. This test was developed 40 yrs ago, and based on a group of people who had known Lyme Disease: they drew their blood and saw what was there and assumed those were typical. Some of the Abs turned out to be specific and some not. Lyme-specific Abs suggests that you've been exposed but not necessarily that the organism is causing your current issues. There is value in testing: does it through labs that are more specific: Global Lyme Diagnostics, IgeneX, Medical Diagnostic Lab in New Jersey. False positives are non-existent. For coinfection testing: same labs for this as well. Thinks it's a good idea to know what you're dealing with.
8. Can you talk about a few key symptoms that will lead you to think of specific coinfections? Bullseye rash or migratory joint pain is Lyme. Nothing else does that. Bartonella: purple/reddish streaks on the skin that look like stretch marks. Most stretch marks with weight loss tend to be clear to opaque. Also tends to have a lot of neuropathy, though that can also be Lyme. Babesia: cyclical fever, hot flushing. Temp doesn't always go up but they'll feel feverish. Air hunger also: don't feel like you're getting a deep breath. Anaplasma, RMSF: unless you get the rash, nothing unique to these.
9. Along those lines: you say CD57 is not Lyme-specific, and while I've certainly heard this too (and have seen exceptions in practice), I have never seen any studies to indicate what other conditions can cause low CD57. Do you know of any in particular? Mold can do this and it can mimic Lyme more than anything else. If people are on Lyme treatment and not responding well, mold would be something they'd look at next. A lot of viruses can cause this as well, and there are some who inherently have low CD57. Most people don't have this tested until they get sick. Viruses can invade the white cells and cause them to go low. He's never found that it correlates with much and doesn't think it's a reliable marker on how they're doing. He stopped doing that a long time ago.
10. Lyme Testing: the questionnaire in Dr Ingels' book is one of the better markers for whether or not you have Lyme. Every lab test can have a false negative. Trying to assess whether you've had exposure: 23, 34, 39, 93. A lot of these are called negative bc they're measuring quantity of Abs, measuring you against a control. The threshold for yes/no is too high. The Lyme screening test is only 43% sensitive.
11. You mention that there is little evidence that Lyme can transmit in utero. I'm surprised by this, as I'd always heard the opposite, and have seen Lyme show up in moms and kids (or at least Lyme specific bands show up on WB in kids and also in spouses of Lyme patients). Can you elaborate on this a bit? This is controversial. In the research, with maternal transmission, kids have higher risks of birth defects. He has worked with families where he's seen children born to mothers with Lyme and seen developmental delays that make him believe they may have acquired Lyme from mom. With Ab testing, if you'll test a child, only IgG passes the placenta so you won't know if that's Mom's or the child's. If you see IgM in the child, that's the child, not mom. There is some maternal transmission: that's his opinion. We all go through the decision of do we treat during pregnancy? He's surprised in some ways that docs may give Abx during pregnancy but won't give herbs. He tends to use the modified Cowden in pregnant women bc there's no evidence of toxicity in the individual herbs. Does recommend pregnant moms get treated if they know they have Lyme disease. In the first 6 mo, you can also see it come over from Mom. Sexual transmission: the research says no. He hasn't seen good evidence of this. It's possible, but unclear. If there's a blood exchange it's possible but unlikely.
12. Do you have any recommended way to test for biofilms internally, or do you just assume they're there with chronic infections and always include them in a Lyme protocol? There's not a great way to test for this. There are some companies that say Dark Field Microscopy. But it's based on our knowledge of Lyme. Presence of biofilms are not abnormal, but Lyme is incredibly good at making biofilms. We do this to give the immune system the best chance.
13. Anything I have not asked: self-care: it's easy to let this slide if you're chronically sick. Get good quality sleep: this is when the body repairs and restores itself. Moving your body: exercise is critical. You can do gentle things like stretching, yoga, etc. He likes this bc it's adaptable to any fitness level. Mental health: if you're chronically ill, this is mentally and emotionally taxing. At some point your friends and family get tired of hearing about it. It's important to establish a support system outside of friends and family: a Lyme support group, a therapist. Make yourself a priority.

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These are some of my notes from our discussion! Dr Aumatma also wants to offer her free e-book, "Diva's Detox Guide" to our listeners. Get yours here!

1. Bio: Dr. Aumatma is a Naturopathic Doctor, with a Master's in Nutrition, who has been practicing medicine for over 10 years. She specializes her practice solely on Fertility, Pregnancy, and Post-Partum, is the best-selling author of "Fertility Secrets: What Your Doctor Didn't Tell You About Baby-Making," and is a sought out speaker on topics of Fertility, Women's Health, and Women's Empowerment. Dr. Aumatma was also awarded the "Best Alternative Medicine Practitioner? award; she consults with clients locally in the Bay Area and works virtually with clients all over the world.
2. Not only do you specialize in fertility?but you are pregnant yourself. Congrats! (Relevant questions here: is this your first? How long have you been planning this, and why now?) Her partner has been ready for 2+ years and she's been putting it off. Last year, she decided she was going to start prepping. It was about 12 mo of preparation. She was using all the tools in her tool kit to maximize and optimize her fertility. Her assumption going in was that if she plans this well enough and prepare well enough, she'd have few symptoms during pregnancy ? and that's how it turned out!
3. What did your "preparation" phase entail: what kind of testing did you undergo in advance, diet changes, supplements, etc? She started running hormone testing for fertility, the nutrient analysis through Spectracell, and food sensitivity testing. In April of last year, pt started having digestive symptoms, and found intestinal permeability. By June or July of last year she was feeling a lot better, best in her life.
4. I understand you're over 35, which puts you, according to traditional medicine, in the "high risk" category. Does this change some of your protocol, both before and during pregnancy? She hasn't done anything different. This is the same protocol that she would run on a 30 or 25 yo to do preconception care. You want to make sure your systems are working. Those are the core: hormones, nutrients, and the gut. The difference comes in with egg and uterine quality. Those are the things that change as you get older. But she's seen 30 yo with poor egg quality: lifestyle, nutrients, alcohol intake, etc. It's just a case by case basis.
5. If you could name the top 3 things any woman could do to prolong fertility, what would they be? 1) get good quality sleep. At the minimum, 6 hours. Can be based on the body type. 6-9. 2) Make sure you're getting good quality, purified water that is not in plastic bottles. Water is crucial to hormone balance and plastics throw off hormones with BPA and all that stuff. 2.5) Make sure your body is not having higher exposures to toxins and for women, especially, most women are walking out with toxic ingredients on the skin. Get products that are free of these hormone imbalancers. 3) Eliminate the alcohol, or at least reduce it. She has heard lots of fertility docs say to cut it out completely. She generally agrees with that, except that it's not likely. 1-2 glasses per week.
6. Is there a specific exercise regimen you would recommend for women to increase their changes of conceiving? A lot of exercises are good, but the one that she really enjoys and likes: 8 min alternating running and walking. 8 min daily, 4-5 times per week. Interval training. That affects HGH which trickles down to affect all hormones.
7. Many career-oriented women over 35yo are hesitant to get pregnant because they hear geriatric pregnancies increases the risk of genetic abnormalities, including Down Syndrome. Can you please shed some light on that? The chances are higher of this when you're older. But her oldest lady that has been pregnant is 44 and she's worked with everything up to that and never seen a case of Down's Syndrome in her practice. But epigenetics plays a role in how our bodies process the nutrients that we have. Make sure your body is optimal regardless of your age.
8. How are you handling some of the pregnancy symptoms? Which ones are you experiencing and what are you doing to deal with them? (Morning sickness, fatigue, etc). She had fatigue for the first 3-4 weeks of pregnancy even before she knew she was pregnant. She just let her body rest. All of her fears kicked in, so she had to do some mind-body healing to process those things. After that, the fatigue lasted another week or two. Then she started taking the prenatal after the positive result and that helped a lot. Nausea: really mild, treated with ginger tea. That resolved itself. Since then she hasn't had a ton of symptoms.
9. For women who have had recurrent miscarriages, what would you say are the top things that you check (and correct) as possible causes? It's important to find the root cause, from miscarriages or not getting pregnant. The patterns she sees: epigenetic or genetic abnormalities, a mutation in certain gene sequences: MTHFR, COMT, VDR are common. The second: making sure egg quality is good. That's where nutrient testing comes in: make sure the woman has the right levels of nutrients. Then gut inflammation. This is the weakest scientific link but she often sees women that have had miscarriages have intestinal permeability.
10. For women who have experienced difficulty getting pregnant, what would you say are the top things that you check (and correct) as possible causes? Same as above. Women who can get pregnant have fewer hormonal imbalances. Low progesterone: you'll have this if you have poor egg quality. Antioxidants, L-Carnitine, CoQ10, vitamin D help to support this. She is less of a fan of DHEA. They almost always get gut symptoms from that, and she has almost never seen it work. If you have low AMH, that won't help it. The other thing they do a lot for egg quality is low level laser therapy. She changes the protocol for out-of-town patients so they can do it in 4 days. This increases egg quality and AMH levels.
11. Would you recommend a technique called seed cycling? If so, have you found it particularly helpful? She likes the technique. She has recommended it to a few women that are borderline hormonal imbalance, but it's not significant enough to justify major interventions. Tends to improve in those cases.
12. Anything else? Get Dr Aumatma's Diva's Detox Guide! http://holisticfertilitycenter.com/divas-detox-guide-2/

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Today's episode is an interview with my colleague, Dr Jillian Stansbury. These are the questions I asked and a paraphrase of Dr Stansbury's answers.

1. Biography: Dr Jillian Stansbury is a naturopathic physician who has practiced in SW Washington for almost 30 years specializing in women's health, mental health, and chronic disease. She holds undergraduate degrees in Medical Illustration and Medical Assisting and graduated with honors in both programs. Dr Stansbury is the former Chair of the Botanical Medicine Program at the National College of Naturopathic Medicine in Portland, OR and remains on the faculty teaching natural products chemistry, botanical influences on cell biology, ethnobotany field course, and other miscellaneous topics in herbal medicine. Dr Stansbury also writes for numerous professional journals and lay publications, plus teaches around the country at a variety of medical and herbal conferences. She frequently travels to Cusco ? "the navel of the world" - and the Peruvian Amazon, studying South American plants and working with various tribes in the jungles of Manu and Iquitos. She is the mother of 2 adult children, enjoys hiking, cooking, music and plays the guitar, banjo, churango and sings, maintains large gardens, and engages in all sorts of arts and crafts.

2. Tell us a little about your book, "Herbal Formularies for Health Professionals, Volume 1: Digestion and Elimination, including the Gastrointestinal System, Liver and Gallbladder, Urinary System, and the Skin." I know it's part of a series of volumes. Can you explain why you grouped these systems all together? These are grouped because they are all "emunctory" organs - organs of elimination. this is the first Volume in a series of practical formulas textbooks, aimed at health professionals because they use medical terminology and discuss quite a bit of chemistry and molecular mechanisms of action. These books are something akin to my life's work, as they represent my 30 years of teaching experience, clinical experience, and decades of keeping abreast of the published studies. The series is 5 volumes all together and is a huge undertaking.

3. Is it better to take botanical medicine with or without meals? It's better to take them with meals if prone to nausea; otherwise, what's most important is just to remember to take them!

4. Cleansing is tremendously popular, and probably the best known herb for liver cleansing in the public is milk thistle. Can you tell us a little about some lesser known liver cleansing herbs and indications for their use? The alteratives: these will alter you for the better. These are bitter roots: dandelion, berberine, rumex. These are cosmopolitan: they grow around the world. Somewhat nourishing but gentle laxatives, gentle stimulants. Many contain inulin: prebiotic. Creates an ecosystem; burdock, dandelion, rumex. Will use these in teas, tinctures. You can make your own dandelion roots from the garden. The bitterness blends well with celery, etc like spinach. The bitterness is desirable too, seems to stimulate saliva flow. To make dandelion from your garden into a tea, you could just rinse them out and chop them into smaller pieces and simmer them in a pot of water and drink them, or save the row you're weeding until you have a small bowl full. Chop, dry, and simmer a tsp of those per cup of hot water.

5. Some great studies have come out indicating that herbal treatments for SIBO are just as effective as the tremendously expensive Rifaximin. What are your favorite herbs for the treatment of SIBO? delayed stomach emptying and gastroparesis: favor motility enhancing herbs. This predisposes to SIBO. Rumex, or yellow dock, contains emotin. Other herbs that contain this are great for motility. Rheum is rhubarb root used in China. 1-2 of those will enhance motility. In other cases, people might develop SIBO bc of stomach acid and reflux and GERD. Sometimes the problem is low stomach acid. Taking vinegar or enzymes might be important for some people. In other cases, getting rid of allergens might help. Demulcent herbs: these have mucilaginous properties, and include aloe, slippery elm, marshmallow, and licorice. These support the barrier function of the stomach.

6. I often use herbs to treat yeast overgrowth and dysbiosis in general, and find it more effective than some of the prescription medications, as well. Can you discuss some of your favorite herbs for these conditions? Diet is essential; it's hard to recover from yeast if you're feeding them with their favorite food: sugar. Berberine is a constituent in a plant, not a plant name. Gets its name from berberis. Mahonia root and berbers are also excellent alternatives and are the source of berberine, as are goldenseal, coptis, etc. There is lots of research on berberine: you can now purchase concentrated berberine against yeast, SIBO, pathogenic bacteria. Essential oils are also great: these could be in the whole food or herb state. All volatile oils are anti-microbial against yeast, candida, etc without harming good bacteria. She likes teas quite a bit for this; gentle, cheap, more prolonged surface contact. 2-3 cups of tea in a row will fill your stomach for 15-20 min and touch every cell in the intestines. A few herbs that are concentrated essential oils: mint oil, peppermint capsules, and oregano oil capsules.

7. If a patient struggles with skin conditions such as acne or eczema or psoriasis, do you have favorite skin cleansing herbs that are a go-to, or do you start by opening their emunctories with liver and gut specific herbs first? For skin conditions, it starts with the gut. One prong of the protocol should be liver and digestive herbs. Diet may be important too. Eczema is more allergic or atopic, so these patients might get more EFAs or things that alter the atopic tendency. Psoriasis is more autoimmune: for these people, look for immune modulating herbs such as reishi, astragalus, etc. But all protocols for people with skin conditions should treat the gut, open emunctories, and improve intestinal dysbiosis. For skin complaints she also likes to add in beta carotene, zinc. For dry, itchy skin, especially good to add EFAs, fish oil or flax seed oil. Zinc and copper are also important for collagen, elastin, etc.

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Today's meditation comes from all of Isaiah 53, the prophecy of the Messiah; but we camp out on Isaiah 53:5. We also briefly jump to Exodus 15:26.To see more about the two Hebrew words we look at, here's shalowm, and here's rapha.Download the latest episode of Christian Natural Health!

Today's podcast comes from this article, Postpartum Depression and Homocysteine. Download the latest episode of Christian Natural Health!

Today's podcast comes from the story of Balaam in Numbers 22-24. We also jump to Revelation 2:14, Deuteronomy 28, and a few other places.Download the latest episode of Christian Natural Health!

Today's episode comes from this article, Inflammatory Markers: CRP, hsCRP and ESRI also reference this article on Inflammation, and this article on the specific immune system and T helper cells.Download the latest episode of Christian Natural Health!

Today's meditation comes from James 1:26 but we're in Proverbs a lot too.Download the latest episode of Christian Natural Health!

Today's podcast comes from this article, Glycemic Index vs Glycemic Load.As promised, here's the chart that helps separate these out.Download the latest episode of Christian Natural Health!

Today's meditation comes from Matthew 6:5-18, when Jesus taught about prayer.Background music courtesy of Ben Sound at www.bensound.comDownload the latest episode of Christian Natural Health!

Today's podcast comes from this article: Your Vagus Nerve: The Key to 'Rest and Digest'As promised, here are some Stress Management Techniques to try.Download the latest episode of Christian Natural Health!

Today's meditation comes from Mark 4:18-20, but we read from Mark 4:1-20.Download the latest episode of Christian Natural Health!

Today's episode comes from this article, "What Our Food Cravings Say About Us." I also reference this article, "Basic Healthy Eating." Download the latest episode of Christian Natural Health!

Today's episode comes from this article, The Benefits of Apple Cider Vinegar.Download the latest episode of Christian Natural Health!

Today's meditation comes from Proverbs 14:23: timeless wisdom for beginning a new year.Download the latest episode of Christian Natural Health!

Today's podcast comes from this article, Spotlight on: L-Theanine.Download the latest episode of Christian Natural Health!

Today's meditation jumps around, but starts in Numbers 24:17, and follows the symbolism of stars: Jesus is the bright morning star, we have the morning star in us, and we are to shine like stars.Background music courtesy of Ben Sound at www.bensound.comDownload the latest episode of Christian Natural Health!

Today's episode comes from this article, Counting Macros.As promised, here is the macro calculator, and here is the body fat percentage calculator. Download the latest episode of Christian Natural Health!

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Today's meditation comes from Isaiah 50:7. We jump around a little bit, mostly to Romans as well.

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Today's podcast comes from this article, "Molecular Mimicry and Autoimmunity."

I also referenced this article, which discusses why Celiac Disease has increased so dramatically since WWII.

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Today we're meditating on 1 Thess 5:16-18 and the concept of thankfulness (and God's will!) in scripture.

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Today's episode comes from this article, "How Your Liver Affects Your Thyroid."

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Today's meditation verse comes from Psalm 119:89-90, but we jump around to a lot of stories in the Old Testament as well.

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This episode comes from this article, "How to Eat On Vacation."

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Today's meditation comes from Hebrews 4:1-11.

I also reference Matthew 8:23-27 where Jesus calms the storm.

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